1 24222216Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others16Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0069 lower (95% confidence interval 0.0045-0.0093); p = 4 × 10−8.
Where it sits Chromosome 12, band 12q14.2 — between genes, 18.4 kb from AVPR1A.
What each result means
A/ATwo copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40436827 · open access
Questions about rs10735914
What is rs10735914?
rs10735914 is a single position in the genome, in or near the near AVPR1A gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10735914 linked to?
On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.
Does having rs10735914 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10735914 come from?
GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 24222216Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others16Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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