0 110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon1Apple0China (ByteDance, Huawei, Baidu…)0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 15,302 Japanese ancestry cases, 76,014 European and East Asian ancestry cases, 36,140 Japanese ancestry controls, 264,785 European and East Asian ancestry controls.
The effect
Each copy of the T allele carried 1.05 times the odds of Coronary artery disease (95% confidence interval 1.03-1.07); p = 4 × 10−11.
How common The T allele had a frequency of about 41% in the people studied.
Where it sits Chromosome 2, band 2p11.2 — in the 3′ untranslated region of VAMP8.
What each result means
C/CNo copy of the version the research linked to Coronary artery disease. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Coronary artery disease. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Circulation. Genomic and precision medicine · 2020 · PMID 32469254
Questions about rs1058588
What is rs1058588?
rs1058588 is a single position in the genome, in or near the VAMP8 gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1058588 linked to?
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs1058588 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1058588 come from?
GWAS Catalog, Circulation. Genomic and precision medicine 2020, PMID:32469254. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon1Apple0China (ByteDance, Huawei, Baidu…)0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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