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Polyunsaturated fatty acid levels

RNF214 · rs1056136

What the study found

Who was studied 239,268 European ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 2 × 10−10.

Where it sits Chromosome 11, band 11q23.3 — in an intron of RNF214.

What each result means

G/G Two copies of the version the research linked to Polyunsaturated fatty acid levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Polyunsaturated fatty acid levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Polyunsaturated fatty acid levels. This is the starting point the study compared everyone against.
Source

Questions about rs1056136

What is rs1056136?

rs1056136 is a single position in the genome, in or near the RNF214 gene. Published research associates it with polyunsaturated fatty acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1056136 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1056136 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Polyunsaturated fatty acid levels (rs1056136). MyGeneLog™. https://www.mygenelog.com/variants/rs1056136

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