Standard
Waist-hip ratio
NFE2L3 · rs1055144
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Waist-hip ratio — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Waist-hip ratio.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Waist-hip ratio compared to the general population.
Source
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Heid IM,
Jackson AU,
Randall JC,
Winkler TW,
Qi L,
Steinthorsdottir V,
Thorleifsson G,
Zillikens MC,
Speliotes EK,
Mägi R,
Workalemahu T,
White CC
and 290 more — show all
Bouatia-Naji N,
Harris TB,
Berndt SI,
Ingelsson E,
Willer CJ,
Weedon MN,
Luan J,
Vedantam S,
Esko T,
Kilpeläinen TO,
Kutalik Z,
Li S,
Monda KL,
Dixon AL,
Holmes CC,
Kaplan LM,
Liang L,
Min JL,
Moffatt MF,
Molony C,
Nicholson G,
Schadt EE,
Zondervan KT,
Feitosa MF,
Ferreira T,
Lango Allen H,
Weyant RJ,
Wheeler E,
Wood AR,
Estrada K,
Goddard ME,
Lettre G,
Mangino M,
Nyholt DR,
Purcell S,
Smith AV,
Visscher PM,
Yang J,
McCarroll SA,
Nemesh J,
Voight BF,
Absher D,
Amin N,
Aspelund T,
Coin L,
Glazer NL,
Hayward C,
Heard-Costa NL,
Hottenga JJ,
Johansson A,
Johnson T,
Kaakinen M,
Kapur K,
Ketkar S,
Knowles JW,
Kraft P,
Kraja AT,
Lamina C,
Leitzmann MF,
McKnight B,
Morris AP,
Ong KK,
Perry JR,
Peters MJ,
Polasek O,
Prokopenko I,
Rayner NW,
Ripatti S,
Rivadeneira F,
Robertson NR,
Sanna S,
Sovio U,
Surakka I,
Teumer A,
van Wingerden S,
Vitart V,
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Cavalcanti-Proença C,
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Fisher E,
Kulzer JR,
Lecoeur C,
Narisu N,
Sandholt C,
Scott LJ,
Silander K,
Stark K,
Tammesoo ML,
Teslovich TM,
Timpson NJ,
Watanabe RM,
Welch R,
Chasman DI,
Cooper MN,
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Pellikka N,
Perola M,
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Alavere H,
Almgren P,
Atwood LD,
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Biffar R,
Bonnycastle LL,
Bornstein SR,
Buchanan TA,
Campbell H,
Day IN,
Dei M,
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Eriksson JG,
Freimer NB,
Fu M,
Gaget S,
Geus EJ,
Gjesing AP,
Grallert H,
Grässler J,
Groves CJ,
Guiducci C,
Hartikainen AL,
Hassanali N,
Havulinna AS,
Herzig KH,
Hicks AA,
Hui J,
Igl W,
Jousilahti P,
Jula A,
Kajantie E,
Kinnunen L,
Kolcic I,
Koskinen S,
Kovacs P,
Kroemer HK,
Krzelj V,
Kuusisto J,
Kvaloy K,
Laitinen J,
Lantieri O,
Lathrop GM,
Lokki ML,
Luben RN,
Ludwig B,
McArdle WL,
McCarthy A,
Morken MA,
Nelis M,
Neville MJ,
Paré G,
Parker AN,
Peden JF,
Pichler I,
Pietiläinen KH,
Platou CG,
Pouta A,
Ridderstråle M,
Samani NJ,
Saramies J,
Sinisalo J,
Smit JH,
Strawbridge RJ,
Stringham HM,
Swift AJ,
Teder-Laving M,
Thomson B,
Usala G,
van Meurs JB,
van Ommen GJ,
Vatin V,
Volpato CB,
Wallaschofski H,
Walters GB,
Widen E,
Wild SH,
Willemsen G,
Witte DR,
Zgaga L,
Zitting P,
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Kähönen M,
Lehtimäki T,
Nieminen MS,
Ohlsson C,
Palmer LJ,
Raitakari O,
Ridker PM,
Stumvoll M,
Tönjes A,
Viikari J,
Balkau B,
Ben-Shlomo Y,
Bergman RN,
Boeing H,
Smith GD,
Ebrahim S,
Froguel P,
Hansen T,
Hengstenberg C,
Hveem K,
Isomaa B,
Jørgensen T,
Karpe F,
Khaw KT,
Laakso M,
Lawlor DA,
Marre M,
Meitinger T,
Metspalu A,
Midthjell K,
Pedersen O,
Salomaa V,
Schwarz PE,
Schwarz PE,
Tuomi T,
Tuomilehto J,
Valle TT,
Wareham NJ,
Arnold AM,
Beckmann JS,
Bergmann S,
Boerwinkle E,
Boomsma DI,
Caulfield MJ,
Collins FS,
Eiriksdottir G,
Gudnason V,
Gyllensten U,
Hamsten A,
Hattersley AT,
Hofman A,
Hu FB,
Illig T,
Iribarren C,
Jarvelin MR,
Kao WH,
Kaprio J,
Launer LJ,
Munroe PB,
Oostra B,
Penninx BW,
Pramstaller PP,
Psaty BM,
Quertermous T,
Rissanen A,
Rudan I,
Shuldiner AR,
Soranzo N,
Spector TD,
Syvanen AC,
Uda M,
Uitterlinden A,
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Abecasis GR,
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Groop LC,
Haritunians T,
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Thorsteinsdottir U,
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Barroso I,
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Nature genetics · 2010 · PMID 20935629
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs1055144
What is rs1055144?
rs1055144 is a single position in the genome, in or near the NFE2L3 gene. Published research associates it with waist-hip ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs1055144?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs1055144 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1055144 come from?
GWAS Catalog, Nat Genet 2010, PMID:20935629. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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