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Vertex-wise cortical thickness

TNIK · rs10513695

What the study found

Who was studied 33,748 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 6.72 z score higher; p = 2 × 10−11.

How common The G allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 3, band 3q26.31 — in an intron of TNIK.

What each result means

G/G Two copies of the version the research linked to Vertex-wise cortical thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Vertex-wise cortical thickness. That is a smaller link than two copies.
T/T No copy of the version the research linked to Vertex-wise cortical thickness. This is the starting point the study compared everyone against.
Source

Questions about rs10513695

What is rs10513695?

rs10513695 is a single position in the genome, in or near the TNIK gene. Published research associates it with vertex-wise cortical thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10513695 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10513695 come from?

GWAS Catalog, Science advances 2021, PMID:34910505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Vertex-wise cortical thickness (rs10513695). MyGeneLog™. https://www.mygenelog.com/variants/rs10513695

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