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Estimated glomerular filtration rate (creatinine, cystatin c)

PPP2R3A · rs10512987

What the study found

Who was studied 406,504 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0285 higher (95% confidence interval 0.024-0.033); p = 2 × 10−39.

Where it sits Chromosome 3, band 3q22.3 — in an intron of PPP2R3A.

What each result means

C/C No copy of the version the research linked to Estimated glomerular filtration rate (creatinine, cystatin c). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Estimated glomerular filtration rate (creatinine, cystatin c). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Estimated glomerular filtration rate (creatinine, cystatin c). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10512987

What is rs10512987?

rs10512987 is a single position in the genome, in or near the PPP2R3A gene. Published research associates it with estimated glomerular filtration rate (creatinine, cystatin c). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10512987 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10512987 come from?

GWAS Catalog, Nature genetics 2024, PMID:39256582. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Estimated glomerular filtration rate (creatinine, cystatin c) (rs10512987). MyGeneLog™. https://www.mygenelog.com/variants/rs10512987

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