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Who was studied 1,640 European ancestry, African American or Afro-Caribbean, NR cases, 756,393 European ancestry, African American or Afro-Caribbean, NR controls; replicated in 189 European ancestry cases, 64,234 European ancestry controls, 101 African American or Afro-Caribbean cases, 12,105 African American or Afro-Caribbean controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 2 × 10−11.
How common The A allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 17, band 17q24.3 — between genes, 105 kb from MYL6P5.
What each result means
A/ATwo copies of the version the research linked to Hidradenitis suppurativa. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Hidradenitis suppurativa. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Hidradenitis suppurativa. This is the starting point the study compared everyone against.
rs10512572 is a single position in the genome, in or near the near MYL6P5 gene. Published research associates it with hidradenitis suppurativa. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10512572 linked to?
On MyGeneLog this position is linked to Hidradenitis Suppurativa. The research behind each link, and its sources, are set out on that condition page.
Does having rs10512572 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10512572 come from?
GWAS Catalog, JAMA dermatology 2023, PMID:37494057. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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