1 362213223120Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others20Total36Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 986 European ancestry cases, 4,946 European ancestry controls; replicated in 1,064 European ancestry cases, 10,082 European ancestry controls.
The effect
Each copy of the A allele carried 1.24 times the odds of Testicular germ cell tumor (95% confidence interval 1.12-1.37); p = 1 × 10−8.
How common The A allele had a frequency of about 69% in the people studied.
Where it sits Chromosome 3, band 3p24.3 — between genes, 3.3 kb from DAZL.
What each result means
A/ATwo copies of the version the research linked to Testicular germ cell tumor. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Testicular germ cell tumor. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Testicular germ cell tumor. This is the starting point the study compared everyone against.
Nature genetics · 2013 · PMID 23666240 · open access
Questions about rs10510452
What is rs10510452?
rs10510452 is a single position in the genome, in or near the DAZL gene. Published research associates it with testicular germ cell tumor. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10510452 linked to?
On MyGeneLog this position is linked to Testicular Germ Cell Tumour. The research behind each link, and its sources, are set out on that condition page.
Does having rs10510452 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10510452 come from?
GWAS Catalog, Nat Genet 2013, PMID:23666240. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 362213223120Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others20Total36Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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