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Depressive symptoms (stressful life events interaction)

RGS10 · rs10510057

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Depressive symptoms (stressful life events interaction) compared to the general population.

C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Depressive symptoms (stressful life events interaction).

G/G Published research associates this genotype with typical/baseline likelihood of Depressive symptoms (stressful life events interaction) — no copies of the reported risk allele.

Source

The First Pilot Genome-Wide Gene-Environment Study of Depression in the Japanese Population

Otowa T, Kawamura Y, Tsutsumi A, Kawakami N, Kan C, Shimada T, Umekage T, Kasai K, Tokunaga K, Sasaki T

PloS one · 2016 · PMID 27529621 · open access

Questions about rs10510057

What is rs10510057?

rs10510057 is a single position in the genome, in or near the RGS10 gene. Published research associates it with depressive symptoms (stressful life events interaction). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10510057 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10510057 come from?

GWAS Catalog, PLoS One 2016, PMID:27529621. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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