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Atrial fibrillation

SH3PXD2A · rs10509768

Where this position leads

Condition: Atrial Fibrillation

rs10509768 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs10509768 rs10509768 SH3PXD2A

What the study found

Who was studied 9,118 East Asian ancestry cases, 33,467 East Asian ancestry controls.

The effect Each copy of the G allele carried 1.20 times the odds of Atrial fibrillation (95% confidence interval 1.14-1.25); p = 9 × 10−16.

Where it sits Chromosome 10, band 10q24.33 — in an intron of SH3PXD2A.

What each result means

A/A No copy of the version the research linked to Atrial fibrillation. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Atrial fibrillation. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10509768

What is rs10509768?

rs10509768 is a single position in the genome, in or near the SH3PXD2A gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10509768 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs10509768 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10509768 come from?

GWAS Catalog, Eur J Clin Invest 2021, PMID:33990960. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation (rs10509768). MyGeneLog™. https://www.mygenelog.com/variants/rs10509768

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