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Microtubule-associated proteins 1A/1B light chain 3A levels

ZCCHC14 · rs1050846

What the study found

Who was studied 2,721 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.177 higher (95% confidence interval 0.13-0.23); p = 3 × 10−11.

How common The A allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 16, band 16q24.2 — a synonymous change in ZCCHC14.

What each result means

A/A Two copies of the version the research linked to Microtubule-associated proteins 1A/1B light chain 3A levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Microtubule-associated proteins 1A/1B light chain 3A levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Microtubule-associated proteins 1A/1B light chain 3A levels. This is the starting point the study compared everyone against.
Source

Questions about rs1050846

What is rs1050846?

rs1050846 is a single position in the genome, in or near the ZCCHC14 gene. Published research associates it with microtubule-associated proteins 1a/1b light chain 3a levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1050846 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1050846 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Microtubule-associated proteins 1A/1B light chain 3A levels (rs1050846). MyGeneLog™. https://www.mygenelog.com/variants/rs1050846

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