LINC00457 · rs10507419
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 345 cases, controls.
The effect Each copy of the A allele carried 1.57 times the odds of Immunoglobulin light chain (AL) amyloidosis (serum Ig lambda profile) (95% confidence interval 1.34-1.85); p = 3 × 10−8.
Where it sits Chromosome 13, band 13q13.2 — in an intron of LINC00457.
rs10507419 is a single position in the genome, in or near the LINC00457 gene. Published research associates it with immunoglobulin light chain (al) amyloidosis (serum ig lambda profile). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Haematologica 2017, PMID:28679651. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.