2 5022127222228Reads by AI crawlersClaude2ChatGPT2Google · Gemini1Perplexity2Meta AI7Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others28Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 329,821 European ancestry individuals; replicated in 122,867 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 6.16 lower (95% confidence interval -); p = 8 × 10−10.
How common The T allele had a frequency of about 94% in the people studied.
Where it sits Chromosome 12, band 12q24.22 — a missense change in SPRING1.
What each result means
C/CNo copy of the version the research linked to Neuroticism. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Neuroticism. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Neuroticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs10507274
What is rs10507274?
rs10507274 is a single position in the genome, in or near the C12orf49 gene. Published research associates it with neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10507274 linked to?
On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs10507274?
Subjects that appear in the title or abstract of the same papers as this rsID include anxiety and worry (2 papers), depression and stress (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs10507274 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10507274 come from?
GWAS Catalog, Nat Genet 2017, PMID:29255261. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 5022127222228Reads by AI crawlersClaude2ChatGPT2Google · Gemini1Perplexity2Meta AI7Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others28Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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