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Corpus callosum genu area

NAV3 · rs10506772

What the study found

Who was studied 46,685 European ancestry individuals; replicated in 4,765 non-European ancestry individuals.

The effect Each copy of the C allele shifted the measure 3.14 lower (95% confidence interval 2.32-3.96); p = 7 × 10−14.

How common The C allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 12, band 12q21.2 — in an intron of NAV3.

What each result means

C/C Two copies of the version the research linked to Corpus callosum genu area. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Corpus callosum genu area. That is a smaller link than two copies.
G/G No copy of the version the research linked to Corpus callosum genu area. This is the starting point the study compared everyone against.
Source

Questions about rs10506772

What is rs10506772?

rs10506772 is a single position in the genome, in or near the NAV3 gene. Published research associates it with corpus callosum genu area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10506772 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10506772 come from?

GWAS Catalog, Nature communications 2025, PMID:41188267. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Corpus callosum genu area (rs10506772). MyGeneLog™. https://www.mygenelog.com/variants/rs10506772

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