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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 875,069 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0043 lower (95% confidence interval 0.0033-0.0053); p = 5 × 10−17.
Where it sits Chromosome 8, band 8p12 — in an intron of GTF2E2.
What ClinVar records
ClassificationBenign; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2018-11-12.
ClinVar record 1261800NM_002095.6(GTF2E2):c.760-298G>A
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CNo copy of the version the research linked to Gamma glutamyl transferase levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Gamma glutamyl transferase levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Gamma glutamyl transferase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2024 · PMID 38632349 · open access
Questions about rs10503871
What is rs10503871?
rs10503871 is a single position in the genome, in or near the GTF2E2 gene. Published research associates it with gamma glutamyl transferase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10503871 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10503871 come from?
GWAS Catalog, Nature genetics 2024, PMID:38632349. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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