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Worry

MADD · rs10501320

What the study found

Who was studied 348,219 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0179 higher (95% confidence interval 0.013-0.023); p = 3 × 10−11.

Where it sits Chromosome 11, band 11p11.2 — in an intron of MADD.

What each result means

C/C Two copies of the version the research linked to Worry. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Worry. That is a smaller link than two copies.
G/G No copy of the version the research linked to Worry. This is the starting point the study compared everyone against.
Source

Questions about rs10501320

What is rs10501320?

rs10501320 is a single position in the genome, in or near the MADD gene. Published research associates it with worry. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10501320 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10501320 come from?

GWAS Catalog, Nat Genet 2018, PMID:29942085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Worry (rs10501320). MyGeneLog™. https://www.mygenelog.com/variants/rs10501320

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