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Fibronectin type III domain-containing protein 5 levels (FNDC5.8041.5.3)

HPX · rs10500671

What the study found

Who was studied 3,301 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.24 higher (95% confidence interval 0.18-0.3); p = 2 × 10−16.

How common The A allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 11, band 11p15.4 — in an intron of HPX.

What each result means

A/A Two copies of the version the research linked to Fibronectin type III domain-containing protein 5 levels (FNDC5.8041.5.3). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Fibronectin type III domain-containing protein 5 levels (FNDC5.8041.5.3). That is a smaller link than two copies.
C/C No copy of the version the research linked to Fibronectin type III domain-containing protein 5 levels (FNDC5.8041.5.3). This is the starting point the study compared everyone against.
Source

Questions about rs10500671

What is rs10500671?

rs10500671 is a single position in the genome, in or near the HPX gene. Published research associates it with fibronectin type iii domain-containing protein 5 levels (fndc5.8041.5.3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10500671 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10500671 come from?

GWAS Catalog, Nature 2018, PMID:29875488. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Fibronectin type III domain-containing protein 5 levels (FNDC5.8041.5.3) (rs10500671). MyGeneLog™. https://www.mygenelog.com/variants/rs10500671

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