Sensitive

Peptic ulcer disease

near CNGA4 · rs10500661

Where this position leads

Condition: Peptic Ulcer Disease

rs10500661 Condition: Peptic Ulcer Disease Peptic Ulcer Disease Condition rs10500661 rs10500661 near CNGA4

What the study found

Who was studied 16,666 European ancestry cases, 439,661 European ancestry controls.

The effect The reported allele is T; the catalogue records no effect size ; p = 4 × 10−14.

How common The T allele had a frequency of about 80% in the people studied.

Where it sits Chromosome 11, band 11p15.4 — between genes, 7.3 kb from CCKBR.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Peptic ulcer disease — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Peptic ulcer disease.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Peptic ulcer disease compared to the general population.
Source

Questions about rs10500661

What is rs10500661?

rs10500661 is a single position in the genome, in or near the near CNGA4 gene. Published research associates it with peptic ulcer disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10500661 linked to?

On MyGeneLog this position is linked to Peptic Ulcer Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs10500661 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10500661 come from?

GWAS Catalog, Nat Commun 2021, PMID:33608531. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Peptic ulcer disease (rs10500661). MyGeneLog™. https://www.mygenelog.com/variants/rs10500661

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