near RNU4-35P · rs10499112
Where this position leads
Condition: Migraine
What the study found
Who was studied 22,500 European ancestry, East Asian ancestry, Hispanic or Latin American, African American or Afro-Caribbean, African ancestry, South Asian ancestry, Other admixed ancestry female cases, 279,762 European ancestry, East Asian ancestry, Hispanic or Latin American, African American or Afro-Caribbean, African ancestry, South Asian ancestry, Other admixed ancestry female controls.
The effect The reported allele is T; the catalogue records no effect size ; p = 9 × 10−11.
How common The T allele had a frequency of about 16% in the people studied.
Where it sits Chromosome 6, band 6q22.31 — between genes, 39.4 kb from RNU4-35P.
rs10499112 is a single position in the genome, in or near the near RNU4-35P gene. Published research associates it with migraine. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Migraine. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Communications biology 2021, PMID:34294844. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Migraine (rs10499112). MyGeneLog™. https://www.mygenelog.com/variants/rs10499112