Sensitive

Urine quinolinate levels in chronic kidney disease

CCNT2 · rs10496732

What the study found

Who was studied 4,908 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.139 lower (95% confidence interval 0.11-0.16); p = 2 × 10−26.

How common The C allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 2, band 2q21.3 — in an intron of CCNT2.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Urine quinolinate levels in chronic kidney disease compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Urine quinolinate levels in chronic kidney disease.
T/T Published research associates this genotype with typical/baseline likelihood of Urine quinolinate levels in chronic kidney disease — no copies of the reported risk allele.
Source

Questions about rs10496732

What is rs10496732?

rs10496732 is a single position in the genome, in or near the CCNT2 gene. Published research associates it with urine quinolinate levels in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10496732 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10496732 come from?

GWAS Catalog, Nature genetics 2023, PMID:37277652. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Urine quinolinate levels in chronic kidney disease (rs10496732). MyGeneLog™. https://www.mygenelog.com/variants/rs10496732

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