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Headache

TGFBR3 · rs10493859

Where this position leads

Condition: Headache

rs10493859 Condition: Headache Headache Condition rs10493859 rs10493859 TGFBR3

What the study found

Who was studied 2,084 Taiwanese ancestry cases, 11,822 Taiwanese ancestry controls.

The effect Each copy of the A allele carried 0.51 times the odds of Headache (95% confidence interval 0.422-0.623); p = 4 × 10−13.

How common The A allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 1, band 1p22.1 — in an intron of TGFBR3.

What each result means

A/A Two copies of the version the research linked to Headache. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Headache. That is a smaller link than two copies.
C/C No copy of the version the research linked to Headache. This is the starting point the study compared everyone against.
Source
Genome-wide association study reveals susceptibility loci for self-reported headache in a large community-based Asian population
Tsao YC, Wang SJ, Hsu CL, Wang YF, Fuh JL, Chen SP, Fann CS
Cephalalgia : an international journal of headache · 2022 · PMID 34404248

Questions about rs10493859

What is rs10493859?

rs10493859 is a single position in the genome, in or near the TGFBR3 gene. Published research associates it with headache. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10493859 linked to?

On MyGeneLog this position is linked to Headache. The research behind each link, and its sources, are set out on that condition page.

Does having rs10493859 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10493859 come from?

GWAS Catalog, Cephalalgia : an international journal of headache 2022, PMID:34404248. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Headache (rs10493859). MyGeneLog™. https://www.mygenelog.com/variants/rs10493859

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