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Height

near PTHLH · rs10492365

Where this position leads

Condition: Height

rs10492365 Condition: Height Height Condition rs10492365 rs10492365 near PTHLH

What the study found

Who was studied 472,730 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0382 higher (95% confidence interval 0.031-0.045); p = 7 × 10−25.

How common The G allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 12, band 12p11.22 — between genes, 10.6 kb from PTHLH.

What each result means

A/A No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Height. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10492365

What is rs10492365?

rs10492365 is a single position in the genome, in or near the near PTHLH gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10492365 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs10492365 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10492365 come from?

GWAS Catalog, Nature 2022, PMID:36224396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs10492365). MyGeneLog™. https://www.mygenelog.com/variants/rs10492365

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