Estimated glomerular filtration rate in non-diabetics
FBXL20 · rs10491128
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 152,624 European ancestry individuals, 36,369 African American individuals.
The effect
Each copy of the A allele shifted the measure 0.461 higher (95% confidence interval 0.35-0.58); p = 4 × 10−15.
How common The A allele had a frequency of about 30% in the people studied.
Where it sits Chromosome 17, band 17q12 — in an intron of FBXL20.
What each result means
A/ATwo copies of the version the research linked to Estimated glomerular filtration rate in non-diabetics. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Estimated glomerular filtration rate in non-diabetics. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Estimated glomerular filtration rate in non-diabetics. This is the starting point the study compared everyone against.
Nature communications · 2019 · PMID 31451708 · open access
Questions about rs10491128
What is rs10491128?
rs10491128 is a single position in the genome, in or near the FBXL20 gene. Published research associates it with estimated glomerular filtration rate in non-diabetics. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10491128 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10491128 come from?
GWAS Catalog, Nature communications 2019, PMID:31451708. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Estimated glomerular filtration rate in non-diabetics (rs10491128). MyGeneLog™. https://www.mygenelog.com/variants/rs10491128