C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Major depressive disorder (stressful life events interaction) compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Major depressive disorder (stressful life events interaction).
T/TPublished research associates this genotype with typical/baseline likelihood of Major depressive disorder (stressful life events interaction) — no copies of the reported risk allele.
The Journal of clinical psychiatry · 2016 · PMID 26845276
Questions about rs10485715
What is rs10485715?
rs10485715 is a single position in the genome, in or near the BMP2 gene. Published research associates it with major depressive disorder (stressful life events interaction). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10485715 linked to?
On MyGeneLog this position is linked to Major Depressive Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs10485715 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10485715 come from?
GWAS Catalog, J Clin Psychiatry 2016, PMID:26845276. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.