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Follicular lymphoma

HLA-DQB1 · rs10484561

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Follicular lymphoma compared to the general population. (GWAS Catalog, Nat Genet 2010, PMID:20639881)
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Follicular lymphoma. (GWAS Catalog, Nat Genet 2010, PMID:20639881)
T/T Published research associates this genotype with typical/baseline likelihood of Follicular lymphoma — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2010, PMID:20639881)

Source: GWAS Catalog, Nat Genet 2010, PMID:20639881

Questions about rs10484561

What is rs10484561?

rs10484561 is a single position in the genome, in or near the HLA-DQB1 gene. Published research associates it with follicular lymphoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10484561 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10484561 come from?

GWAS Catalog, Nat Genet 2010, PMID:20639881. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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