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Hepatitis

CASC15 · rs10484389

Where this position leads

Condition: Chronic Hepatitis C

rs10484389 Condition: Chronic Hepatitis C Chronic Hepatitis C Condition rs10484389 rs10484389 CASC15

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Hepatitis — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hepatitis.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hepatitis compared to the general population.
Source
Genome-wide association study of hepatitis in korean populations
Hong Y, Oh S
Genomics & informatics · 2014 · PMID 25705159 · open access

Questions about rs10484389

What is rs10484389?

rs10484389 is a single position in the genome, in or near the CASC15 gene. Published research associates it with hepatitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10484389 linked to?

On MyGeneLog this position is linked to Chronic Hepatitis C. The research behind each link, and its sources, are set out on that condition page.

Does having rs10484389 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10484389 come from?

GWAS Catalog, Genomics Inform 2014, PMID:25705159. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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