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Neutrophil percentage of white cells

RAD50 · rs10479009

Where this position leads

Condition: Blood Cell Counts

rs10479009 Condition: Blood Cell Counts Blood Cell Counts Condition rs10479009 rs10479009 RAD50

What the study found

Who was studied 171,542 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0275 lower (95% confidence interval 0.018-0.036); p = 2 × 10−9.

How common The G allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 5, band 5q31.1 — in an intron of RAD50.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Neutrophil percentage of white cells compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Neutrophil percentage of white cells.
T/T Published research associates this genotype with typical/baseline likelihood of Neutrophil percentage of white cells — no copies of the reported risk allele.
Source

Questions about rs10479009

What is rs10479009?

rs10479009 is a single position in the genome, in or near the RAD50 gene. Published research associates it with neutrophil percentage of white cells. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10479009 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs10479009 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10479009 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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