0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 44,214 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.04 higher; p = 1 × 10−9.
How common The T allele had a frequency of about 30% in the people studied.
Where it sits Chromosome 5, band 5q23.1 — between genes, 12.1 kb from TNFAIP8.
What each result means
C/CNo copy of the version the research linked to Alpha angle. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Alpha angle. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Alpha angle. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs10478422 is a single position in the genome, in or near the near TNFAIP8 gene. Published research associates it with alpha angle. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10478422 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10478422 come from?
GWAS Catalog, Arthritis & rheumatology (Hoboken, N.J.) 2023, PMID:36662418. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.