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Edge-level brain connectivity (multivariate analysis)

near RPL35AP15 · rs10478336

What the study found

Who was studied 30,810 British ancestry individuals.

The effect Each copy of the A allele shifted the measure 7.23 z score higher; p = 5 × 10−13.

How common The A allele had a frequency of about 73% in the people studied.

Where it sits Chromosome 5, band 5q23.1 — between genes, 90.6 kb from RPL35AP15.

What each result means

A/A Two copies of the version the research linked to Edge-level brain connectivity (multivariate analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Edge-level brain connectivity (multivariate analysis). That is a smaller link than two copies.
G/G No copy of the version the research linked to Edge-level brain connectivity (multivariate analysis). This is the starting point the study compared everyone against.
Source

Questions about rs10478336

What is rs10478336?

rs10478336 is a single position in the genome, in or near the near RPL35AP15 gene. Published research associates it with edge-level brain connectivity (multivariate analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10478336 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10478336 come from?

GWAS Catalog, Science advances 2023, PMID:36800424. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Edge-level brain connectivity (multivariate analysis) (rs10478336). MyGeneLog™. https://www.mygenelog.com/variants/rs10478336

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