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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 3,513 north-western European ancestry individuals; replicated in 599 north-western European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 5.6 z score lower; p = 2 × 10−8.
How common The T allele had a frequency of about 94% in the people studied.
Where it sits Chromosome 5, band 5q33.1 — between genes, 7.5 kb from NMUR2.
What each result means
C/CNo copy of the version the research linked to Facial wrinkles. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Facial wrinkles. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Facial wrinkles. That is the strongest link of the three results. A link in a study is not a diagnosis.
The Journal of investigative dermatology · 2018 · PMID 29555444
Questions about rs10476781
What is rs10476781?
rs10476781 is a single position in the genome, in or near the near NMUR2 gene. Published research associates it with facial wrinkles. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10476781 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10476781 come from?
GWAS Catalog, The Journal of investigative dermatology 2018, PMID:29555444. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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