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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 125,000 African ancestry individuals (MTAG boosted by total cholesterol and high-density lipoprotein samples).
The effect
Each copy of the T allele shifted the measure 0.038 lower (95% confidence interval 0.026-0.05); p = 6 × 10−11.
Where it sits Chromosome 5, band 5q33.3 — in an intron of TIMD4.
What each result means
C/CNo copy of the version the research linked to Triglyceride levels (MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Triglyceride levels (MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Triglyceride levels (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2023 · PMID 37669986 · open access
Questions about rs10475859
What is rs10475859?
rs10475859 is a single position in the genome, in or near the TIMD4 gene. Published research associates it with triglyceride levels (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10475859 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10475859 come from?
GWAS Catalog, Nature communications 2023, PMID:37669986. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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