Standard
Hip minimal joint space width
PIK3R1 · rs10471753
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hip minimal joint space width compared to the general population.
C/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hip minimal joint space width.
G/G
Published research associates this genotype with typical/baseline likelihood of Hip minimal joint space width — no copies of the reported risk allele.
Source
Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis
Castaño-Betancourt MC,
Evans DS,
Ramos YF,
Boer CG,
Metrustry S,
Liu Y,
den Hollander W,
van Rooij J,
Kraus VB,
Yau MS,
Mitchell BD,
Muir K
and 25 more — show all
Hofman A,
Doherty M,
Doherty S,
Zhang W,
Kraaij R,
Rivadeneira F,
Barrett-Connor E,
Maciewicz RA,
Arden N,
Nelissen RG,
Kloppenburg M,
Jordan JM,
Nevitt MC,
Slagboom EP,
Hart DJ,
Lafeber F,
Styrkarsdottir U,
Zeggini E,
Evangelou E,
Spector TD,
Uitterlinden AG,
Lane NE,
Meulenbelt I,
Valdes AM,
van Meurs JB
PLoS genetics · 2016 · PMID 27701424 · open access
Questions about rs10471753
What is rs10471753?
rs10471753 is a single position in the genome, in or near the PIK3R1 gene. Published research associates it with hip minimal joint space width. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10471753 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10471753 come from?
GWAS Catalog, PLoS Genet 2016, PMID:27701424. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants