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X-12093 levels

ALMS1 · rs10469966

What the study found

Who was studied 2,854 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.102 higher (95% confidence interval 0.088-0.116); p = 1 × 10−51.

How common The A allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 2, band 2p13.1 — in an intron of ALMS1.

What each result means

A/A Two copies of the version the research linked to X-12093 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to X-12093 levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to X-12093 levels. This is the starting point the study compared everyone against.
Source

Questions about rs10469966

What is rs10469966?

rs10469966 is a single position in the genome, in or near the ALMS1 gene. Published research associates it with x-12093 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10469966 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10469966 come from?

GWAS Catalog, Nature genetics 2014, PMID:24816252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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X-12093 levels (rs10469966). MyGeneLog™. https://www.mygenelog.com/variants/rs10469966

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