Tumor necrosis factor-inducible gene 6 protein levels
TNFAIP6 · rs1046668
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 997 European ancestry individuals; replicated in 338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.402 lower (95% confidence interval 0.29-0.52); p = 2 × 10−11.
Where it sits Chromosome 2, band 2q23.3 — a missense change in TNFAIP6.
What each result means
A/ANo copy of the version the research linked to Tumor necrosis factor-inducible gene 6 protein levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Tumor necrosis factor-inducible gene 6 protein levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Tumor necrosis factor-inducible gene 6 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2017 · PMID 28240269 · open access
Questions about rs1046668
What is rs1046668?
rs1046668 is a single position in the genome, in or near the TNFAIP6 gene. Published research associates it with tumor necrosis factor-inducible gene 6 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1046668 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1046668 come from?
GWAS Catalog, Nature communications 2017, PMID:28240269. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Tumor necrosis factor-inducible gene 6 protein levels (rs1046668). MyGeneLog™. https://www.mygenelog.com/variants/rs1046668