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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 10,708 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.098 lower (95% confidence interval 0.067-0.129); p = 2 × 10−9.
How common The A allele had a frequency of about 69% in the people studied.
Where it sits Chromosome 1, band 1q21.3 — in an intron of TDRD10.
What each result means
A/ATwo copies of the version the research linked to Interleukin-6 receptor subunit alpha levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Interleukin-6 receptor subunit alpha levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Interleukin-6 receptor subunit alpha levels. This is the starting point the study compared everyone against.
rs10465961 is a single position in the genome, in or near the TDRD10 gene. Published research associates it with interleukin-6 receptor subunit alpha levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10465961 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10465961 come from?
GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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