Standard

Forced expiratory volume (baseline)

near ZNF322 · rs10456333

What the study found

Who was studied 373,397 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0352 lower (95% confidence interval 0.023-0.048); p = 2 × 10−8.

How common The G allele had a frequency of about 96% in the people studied.

Where it sits Chromosome 6, band 6p22.2 — between genes, 27.6 kb from ZNF322.

What each result means

A/A No copy of the version the research linked to Forced expiratory volume (baseline). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Forced expiratory volume (baseline). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Forced expiratory volume (baseline). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10456333

What is rs10456333?

rs10456333 is a single position in the genome, in or near the near ZNF322 gene. Published research associates it with forced expiratory volume (baseline). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10456333 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10456333 come from?

GWAS Catalog, Nature communications 2025, PMID:40374629. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Forced expiratory volume (baseline) (rs10456333). MyGeneLog™. https://www.mygenelog.com/variants/rs10456333

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