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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 7,125 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.113 lower; p = 2 × 10−11.
Where it sits Chromosome 1, band 1p34.2 — between genes, 23.4 kb from Y_RNA.
What each result means
C/CNo copy of the version the research linked to Lysophosphatidylcholines (FA16:0) (Model 2). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Lysophosphatidylcholines (FA16:0) (Model 2). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Lysophosphatidylcholines (FA16:0) (Model 2). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2026 · PMID 42069741 · open access
Questions about rs10443218
What is rs10443218?
rs10443218 is a single position in the genome, in or near the near Y_RNA gene. Published research associates it with lysophosphatidylcholines (fa16:0) (model 2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10443218 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10443218 come from?
GWAS Catalog, Nature communications 2026, PMID:42069741. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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