C/CPublished research associates this genotype with typical/baseline likelihood of Menarche (age at onset) — no copies of the reported risk allele. (GWAS Catalog, Hum Mol Genet 2013, PMID:23599027)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Menarche (age at onset). (GWAS Catalog, Hum Mol Genet 2013, PMID:23599027)
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Menarche (age at onset) compared to the general population. (GWAS Catalog, Hum Mol Genet 2013, PMID:23599027)
rs10441737 is a single position in the genome, in or near the ZNF483 gene. Published research associates it with menarche (age at onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10441737 linked to?
On MyGeneLog this position is linked to Age at Menarche. The research behind each link, and its sources, are set out on that condition page.
Does having rs10441737 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10441737 come from?
GWAS Catalog, Hum Mol Genet 2013, PMID:23599027. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.