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Immunoglobulin A levels

near TTC33 · rs10440635

What the study found

Who was studied 85,204 European or unknown ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0341 SD unit higher (95% confidence interval 0.024-0.044); p = 5 × 10−12.

Where it sits Chromosome 5, band 5p13.1 — between genes, 21.6 kb from TTC33.

What each result means

A/A Two copies of the version the research linked to Immunoglobulin A levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Immunoglobulin A levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Immunoglobulin A levels. This is the starting point the study compared everyone against.
Source

Questions about rs10440635

What is rs10440635?

rs10440635 is a single position in the genome, in or near the near TTC33 gene. Published research associates it with immunoglobulin a levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10440635 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10440635 come from?

GWAS Catalog, Genes and immunity 2026, PMID:42642615. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Immunoglobulin A levels (rs10440635). MyGeneLog™. https://www.mygenelog.com/variants/rs10440635

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