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Pulse pressure

near LINC01808 · rs10439377

What the study found

Who was studied 526,001 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.149 lower (95% confidence interval 0.1-0.198); p = 2 × 10−9.

Where it sits Chromosome 2, band 2p24.1 — between genes, 65.6 kb from LINC01808.

What each result means

C/C No copy of the version the research linked to Pulse pressure. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Pulse pressure. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Pulse pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10439377

What is rs10439377?

rs10439377 is a single position in the genome, in or near the near LINC01808 gene. Published research associates it with pulse pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10439377 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10439377 come from?

GWAS Catalog, Investigative ophthalmology & visual science 2022, PMID:35762941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Pulse pressure (rs10439377). MyGeneLog™. https://www.mygenelog.com/variants/rs10439377

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