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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 10,768 European ancestry infants; replicated in 8,321 European ancestry infants.
The effect
Each copy of the T allele shifted the measure 0.065 SD lower (95% confidence interval 0.045-0.085); p = 3 × 10−10.
How common The T allele had a frequency of about 49% in the people studied.
Where it sits Chromosome 12, band 12q14.3 — in the 3′ untranslated region of HMGA2.
What each result means
C/CNo copy of the version the research linked to Head circumference (infant). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Head circumference (infant). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Head circumference (infant). That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs1042725
What is rs1042725?
rs1042725 is a single position in the genome, in or near the HMGA2 gene. Published research associates it with head circumference (infant). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs1042725?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers), bones and fractures (1 papers), vitamins and nutrient levels (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs1042725 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1042725 come from?
GWAS Catalog, Nat Genet 2012, PMID:22504419. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Head circumference (infant) (rs1042725). MyGeneLog™. https://www.mygenelog.com/variants/rs1042725