Leukocyte immunoglobulin-like receptor subfamily B member 1 level in Chronic kidney disease with hypertension and no diabetes (5090_49)
LILRB1 · rs10427127
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 466 African American individuals.
The effect
Each copy of the C allele shifted the measure 1.03 lower (95% confidence interval 0.93-1.13); p = 3 × 10−103.
How common The C allele had a frequency of about 37% in the people studied.
Where it sits Chromosome 19, band 19q13.42 — a synonymous change in LILRB1.
What each result means
C/CTwo copies of the version the research linked to Leukocyte immunoglobulin-like receptor subfamily B member 1 level in Chronic kidney disease with hypertension and no diabetes (5090_49). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Leukocyte immunoglobulin-like receptor subfamily B member 1 level in Chronic kidney disease with hypertension and no diabetes (5090_49). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Leukocyte immunoglobulin-like receptor subfamily B member 1 level in Chronic kidney disease with hypertension and no diabetes (5090_49). This is the starting point the study compared everyone against.
rs10427127 is a single position in the genome, in or near the LILRB1 gene. Published research associates it with leukocyte immunoglobulin-like receptor subfamily b member 1 level in chronic kidney disease with hypertension and no diabetes (5090_49). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10427127 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10427127 come from?
GWAS Catalog, Kidney international 2022, PMID:35870639. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Leukocyte immunoglobulin-like receptor subfamily B member 1 level in Chronic kidney disease with hypertension and no diabetes (5090_49) (rs10427127). MyGeneLog™. https://www.mygenelog.com/variants/rs10427127