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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 443,734 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0252 higher (95% confidence interval 0.021-0.03); p = 3 × 10−26.
How common The A allele had a frequency of about 21% in the people studied.
Where it sits Chromosome 19, band 19q13.41 — in the 3′ untranslated region of KLK10.
What each result means
A/ATwo copies of the version the research linked to Serum 25-Hydroxyvitamin D levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Serum 25-Hydroxyvitamin D levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Serum 25-Hydroxyvitamin D levels. This is the starting point the study compared everyone against.
American journal of human genetics · 2020 · PMID 32059762
Questions about rs10426
What is rs10426?
rs10426 is a single position in the genome, in or near the KLK10 gene. Published research associates it with serum 25-hydroxyvitamin d levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10426 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10426 come from?
GWAS Catalog, American journal of human genetics 2020, PMID:32059762. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Serum 25-Hydroxyvitamin D levels (rs10426). MyGeneLog™. https://www.mygenelog.com/variants/rs10426