A/APublished research associates this genotype with typical/baseline likelihood of Basal cell carcinoma — no copies of the reported risk allele. (GWAS Catalog, Nat Commun 2016, PMID:27539887)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Basal cell carcinoma. (GWAS Catalog, Nat Commun 2016, PMID:27539887)
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Basal cell carcinoma compared to the general population. (GWAS Catalog, Nat Commun 2016, PMID:27539887)
Nature communications · 2016 · PMID 27539887 · open access
Questions about rs10425559
What is rs10425559?
rs10425559 is a single position in the genome, in or near the PLIN3 gene. Published research associates it with basal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10425559 linked to?
On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs10425559 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10425559 come from?
GWAS Catalog, Nat Commun 2016, PMID:27539887. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.