APOC2 · rs10420434
Where this position leads
Condition: C-Reactive Protein Levels
What the study found
Who was studied 575,531 European ancestry individuals.
The effect Each copy of the A allele shifted the measure 0.043 higher (95% confidence interval 0.034-0.052); p = 3 × 10−20.
Where it sits Chromosome 19, band 19q13.32 — in the 5′ untranslated region of APOC2.
rs10420434 is a single position in the genome, in or near the APOC2 gene. Published research associates it with c-reactive protein levels (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature communications 2022, PMID:36376304. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
C-reactive protein levels (MTAG) (rs10420434). MyGeneLog™. https://www.mygenelog.com/variants/rs10420434