Standard
Cholesterol, total
APOB · rs1041968
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cholesterol, total compared to the general population. (GWAS Catalog, Nat Genet 2015, PMID:25961943)
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cholesterol, total. (GWAS Catalog, Nat Genet 2015, PMID:25961943)
G/G
Published research associates this genotype with typical/baseline likelihood of Cholesterol, total — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2015, PMID:25961943)
Source
The impact of low-frequency and rare variants on lipid levels
Surakka I,
Horikoshi M,
Mägi R,
Sarin AP,
Mahajan A,
Lagou V,
Marullo L,
Ferreira T,
Miraglio B,
Timonen S,
Kettunen J,
Pirinen M
and 74 more — show all
Karjalainen J,
Thorleifsson G,
Hägg S,
Hottenga JJ,
Isaacs A,
Ladenvall C,
Beekman M,
Esko T,
Ried JS,
Nelson CP,
Willenborg C,
Gustafsson S,
Westra HJ,
Blades M,
de Craen AJ,
de Geus EJ,
Deelen J,
Grallert H,
Hamsten A,
Havulinna AS,
Hengstenberg C,
Houwing-Duistermaat JJ,
Hyppönen E,
Karssen LC,
Lehtimäki T,
Lyssenko V,
Magnusson PK,
Mihailov E,
Müller-Nurasyid M,
Mpindi JP,
Pedersen NL,
Penninx BW,
Perola M,
Pers TH,
Peters A,
Rung J,
Smit JH,
Steinthorsdottir V,
Tobin MD,
Tsernikova N,
van Leeuwen EM,
Viikari JS,
Willems SM,
Willemsen G,
Schunkert H,
Erdmann J,
Samani NJ,
Kaprio J,
Lind L,
Gieger C,
Metspalu A,
Slagboom PE,
Groop L,
van Duijn CM,
Eriksson JG,
Jula A,
Salomaa V,
Boomsma DI,
Power C,
Raitakari OT,
Ingelsson E,
Järvelin MR,
Thorsteinsdottir U,
Franke L,
Ikonen E,
Kallioniemi O,
Pietiäinen V,
Lindgren CM,
Stefansson K,
Palotie A,
McCarthy MI,
Morris AP,
Prokopenko I,
Ripatti S
Nature genetics · 2015 · PMID 25961943
Questions about rs1041968
What is rs1041968?
rs1041968 is a single position in the genome, in or near the APOB gene. Published research associates it with cholesterol, total. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1041968 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1041968 come from?
GWAS Catalog, Nat Genet 2015, PMID:25961943. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants