3 46325223128Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity0Meta AI5Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others28Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied up to 62,166 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.095 s.d. higher (95% confidence interval 0.083-0.107); p = 5 × 10−54.
How common The A allele had a frequency of about 48% in the people studied.
Where it sits Chromosome 2, band 2p24.1 — a synonymous change in APOB.
What ClinVar records
ClassificationBenign for Hypercholesterolemia, autosomal dominant, type B, Familial hypobetalipoproteinemia 1, Familial hypercholesterolemia, Cardiovascular phenotype; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 12 submitters), last evaluated 2026-01-27.
ClinVar record 1169879NM_000384.3(APOB):c.6936C>T (p.Asp2312=)
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ATwo copies of the version the research linked to Cholesterol, total. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Cholesterol, total. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Cholesterol, total. This is the starting point the study compared everyone against.
rs1041968 is a single position in the genome, in or near the APOB gene. Published research associates it with cholesterol, total. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1041968 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs1041968 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1041968 come from?
GWAS Catalog, Nat Genet 2015, PMID:25961943. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 46325223128Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity0Meta AI5Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others28Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cholesterol, total (rs1041968). MyGeneLog™. https://www.mygenelog.com/variants/rs1041968