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Total concentration of 19 human milk oligosaccharides

near SEC1P · rs10414887

What the study found

Who was studied 764 European ancestry individuals, 48 South Asian ancestry individuals, 126 East Asian ancestry individuals, 26 African American or Afro-Caribbean individuals, 16 Other admixed ancestry and unknown ancestry individuals; replicated in 395 individuals.

The effect Each copy of the A allele shifted the measure 6.12 zscore higher; p = 9 × 10−10.

Where it sits Chromosome 19, band 19q13.33 — between genes, 3.5 kb from SEC1P.

What each result means

A/A Two copies of the version the research linked to Total concentration of 19 human milk oligosaccharides. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Total concentration of 19 human milk oligosaccharides. That is a smaller link than two copies.
G/G No copy of the version the research linked to Total concentration of 19 human milk oligosaccharides. This is the starting point the study compared everyone against.
Source

Questions about rs10414887

What is rs10414887?

rs10414887 is a single position in the genome, in or near the near SEC1P gene. Published research associates it with total concentration of 19 human milk oligosaccharides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10414887 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10414887 come from?

GWAS Catalog, Nature communications 2024, PMID:39232002. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total concentration of 19 human milk oligosaccharides (rs10414887). MyGeneLog™. https://www.mygenelog.com/variants/rs10414887

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