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Basal ganglia structure

ARHGAP35 · rs10414860

What the study found

Who was studied 34,794 British ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 1 × 10−11.

Where it sits Chromosome 19, band 19q13.32 — in an intron of ARHGAP35.

What each result means

A/A No copy of the version the research linked to Basal ganglia structure. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Basal ganglia structure. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Basal ganglia structure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10414860

What is rs10414860?

rs10414860 is a single position in the genome, in or near the ARHGAP35 gene. Published research associates it with basal ganglia structure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10414860 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10414860 come from?

GWAS Catalog, Nature communications 2024, PMID:39353893. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Basal ganglia structure (rs10414860). MyGeneLog™. https://www.mygenelog.com/variants/rs10414860

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