Sensitive

Lung adenocarcinoma

near SPRED2 · rs1039766

Where this position leads

Condition: EGFR Mutation-Positive Lung Adenocarcinoma

rs1039766 Condition: EGFR Mutation-Positive Lung Adenocarcinoma EGFR Mutation-Positive Lung Adenoca… Condition rs1039766 rs1039766 near SPRED2

What the study found

Who was studied 12,346 East Asian ancestry cases, 225,690 East Asian ancestry controls, 10,976 European ancestry cases, 260,520 European ancestry controls.

The effect Each copy of the T allele carried 1.12 times the odds of Lung adenocarcinoma (95% confidence interval 1.08-1.15); p = 3 × 10−12.

How common The T allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 2, band 2p14 — between genes, 17.8 kb from SPRED2.

What each result means

C/C No copy of the version the research linked to Lung adenocarcinoma. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Lung adenocarcinoma. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Lung adenocarcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1039766

What is rs1039766?

rs1039766 is a single position in the genome, in or near the near SPRED2 gene. Published research associates it with lung adenocarcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1039766 linked to?

On MyGeneLog this position is linked to EGFR Mutation-Positive Lung Adenocarcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs1039766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1039766 come from?

GWAS Catalog, Genome medicine 2026, PMID:42152146. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lung adenocarcinoma (rs1039766). MyGeneLog™. https://www.mygenelog.com/variants/rs1039766

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