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Cerebrospinal fluid t-tau:AB1-42 ratio

LOC100129104 · rs1036819

What the study found

Who was studied 3,146 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 5 × 10−9.

How common The C allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 8, band 8q24.22 — in an intron of ZFAT-AS1.

What each result means

A/A No copy of the version the research linked to Cerebrospinal fluid t-tau:AB1-42 ratio. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Cerebrospinal fluid t-tau:AB1-42 ratio. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Cerebrospinal fluid t-tau:AB1-42 ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1036819

What is rs1036819?

rs1036819 is a single position in the genome, in or near the LOC100129104 gene. Published research associates it with cerebrospinal fluid t-tau:ab1-42 ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1036819 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1036819 come from?

GWAS Catalog, Alzheimers Res Ther 2018, PMID:30153862. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cerebrospinal fluid t-tau:AB1-42 ratio (rs1036819). MyGeneLog™. https://www.mygenelog.com/variants/rs1036819

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